Glycosylation

Glycosylation represents another important type of post-translational modification. Glycans serve a variety of structural and functional roles in membranes and secreted proteins.  

Generally, serine, threonine, and asparagine residues are suitable amino acids for glycosylation.

BIOSYNTAN offers various types of glycosyl-residues at those amino acids. An overview is presented in the following table. For any other type of glycosylation, please inquire. 

Ser-typeThr-type Asn-type
Ser(α-D-GalNAc)Thr(α-D-GalNAc)Asn(β-D-GlcNAc)
Ser(β-D-GalNAc)Thr(β-D-GalNAc)Asn(Gal)
Ser(α-D-Man)Thr(α-D-Man)Asn(Glc)
Ser(β-D-Gal)Thr(β-D-GlcNAc)
Ser(β-D-Glc)Thr(STn)
Ser(β-D-GlcNAc)Thr(TF)
Ser(STn)
Ser(TF)