Glycosylation represents another important type of post-translational modification. Glycans serve a variety of structural and functional roles in membranes and secreted proteins.
Generally, serine, threonine, and asparagine residues are suitable amino acids for glycosylation.
BIOSYNTAN offers various types of glycosyl-residues at those amino acids. An overview is presented in the following table. For any other type of glycosylation, please inquire.
| Ser-type | Thr-type | Asn-type |
|---|---|---|
| Ser(α-D-GalNAc) | Thr(α-D-GalNAc) | Asn(β-D-GlcNAc) |
| Ser(β-D-GalNAc) | Thr(β-D-GalNAc) | Asn(Gal) |
| Ser(α-D-Man) | Thr(α-D-Man) | Asn(Glc) |
| Ser(β-D-Gal) | Thr(β-D-GlcNAc) | |
| Ser(β-D-Glc) | Thr(STn) | |
| Ser(β-D-GlcNAc) | Thr(TF) | |
| Ser(STn) | ||
| Ser(TF) |