Ubiquitin & Derivatives

The small protein ubiquitin plays an important role in a variety of cell processes, e.g. in degradation of misfolded proteins, in signal transduction, and regulation of transcription. For all of these reasons, there has been increased research focused on ubiquitin.

Fluorescently labeled variants of ubiquitin are particularly interesting for localization studies. Rhodamine 110 derivatives are suitable tools for the investigation of deubiquitinating enzymes. Different modification at the C-terminus complete the portfolio of BIOSYNTAN:

 

ubiquitin-AMC
ubiquitin-Rh110-D-Pro
ubiquitin-Rh110-γ-Glu
ubiquitin-hydroxamate

BIOSYNTAN offers ubiquitin and fluorescently labeled derivatives in very high quality. Purities of >95% are proved by HPLC and MS. BIOSYNTAN provides quantities up to 100 mg.